This invention provides a novel disubstituted 1,2,4-triazine compound or a pharmaceutically acceptable salt thereof, which has an aldosterone synthetase inhibitory activity and is useful for preventing and/or treating various diseases or conditions associated with aldosterone； a method for preparing it； use of it； as well as a pharmaceutical composition comprising it as an active ingredient. A compound of the general formula [I]:wherein RA is, for example, a group of the following formula (A-1):wherein ring A1 is, for example, a cycloalkyl group which may be substituted,and RB is, for example, a monocyclic cycloalkyl group,or a pharmaceutically acceptable salt thereof.
