Systems and method are provided that enable a spectrophotometric system to obtain reasonably reliable measurements even in situations when some of the emitters included in a sensor system have become inoperable. In certain embodiments, the spectrophotometric system may include two or more light emitters. The light emitters may be used to derive measurements suitable for pulse oximetry, hemometry, and/or aquametry. The failure of one or more of the emitters may still allow for the derivation of certain measurements by using the emitters that remain in an operational state.