KINNEY, WILLIAM A.,MACHATHA, STEPHEN GITU,YOUNG, SCOTT
申请号:
CA3032609
公开号:
CA3032609A1
申请日:
2017.08.22
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention provides compounds and methods for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.