New agents for the treatment of cancer

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专利权人:

发明人:

申请号：

EP14161424.8

公开号：

EP2924045A1

申请日:

2014.03.25

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention relates to compounds comprising a Co3+ ion and a tyrosine kinase inhibitor moiety, wherein the tyrosine kinase inhibitor moiety comprises a Co3+-chelating moiety and wherein the tyrosine kinase inhibitor moiety is a 4-anilinoquinazoline tyrosine kinase inhibitor moiety. The 4-anilinoquinazoline tyrosine kinase inhibitor moiety has the general formula B, wherein R1, R2, R3 and m are as defined herein. The compounds are useful in the treatment of hyperproliferative diseases, such as cancer.

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