The present invention relates to a novel manufacturing method of an aryl naphthalene lignan compound. For the aryl naphthalene lignan-type compound and derivative synthesis of the present invention, a naphthalene skeleton center is built at first and an aryl group can be introduced during the final stage. In this way, various derivatives can be effectively synthesized, and the method is also suitable for mass production.본 발명은 아릴 나프탈렌 리그난 화합물의 신규한 제조방법에 관한 것이다.