The present invention provides a kind of sustained release preparations comprising Pioglitazone or its salt as active constituent, show good slow release effect. Sustained release preparation comprising Pioglitazone or its salt, show 2 hour time point there is average 25-58% to dissolve out ratio, 4 hour time point there is average 60-100% to dissolve out ratio, dissolution experiment is according to 50rpm United States Pharmacopeias paddle method and using in 37 DEG C of pH2.0KCl/HCl buffers are as experimental solutions.本發明提供了一種包含吡格列酮或其鹽作爲活性成分的緩釋製劑,表現出很好的緩釋效果。包含吡格列酮或其鹽的緩釋製劑,表現出在2小時時間點具有平均25-58%溶出比例,在4小時時間點具有平均60-100%溶出比例,溶出實驗根據50rpm美國藥典槳葉方法且使用在37℃的pH2.0KCl/HCl緩衝液作爲實驗溶液。
