The present invention relates to a magnetic field applicator for use in hyperthermia employing magnetic particles, for destroying tumour tissues. The system comprises an electromagnet assembly, which can be driven with a variable frequency power source via an electrical coupling circuit. The electromagnet is composed of a pair of identical copper coils, a soft-ferrite yoke and a pair of identical pole shoes, with the physical layout of the individual components arranged/designed such that the a maximally efficient localized homogeneous heating of the biological tissue is obtained. It produces a sinusoidally oscillating magnetic field in the frequency range of 10 kHz to 500 kHz, with maximum amplitude of 20 kAm"1. This applicator is suitable for hyperthermia using a wide range of size of magnetic particles ranging from a few nanometers to a few millimeters. These magnetic particles, which are transducers for converting magnetic energy into thermal energy, could be as immobilized in the biological tissue or as dispersed in a liquid medium or in solid state. Also, the use of surface-functionalized, nanometer-sized magnetic particles to generate in-vitro or in-vivo hyperthermia for Nanotechnological and Nanomedical applications are envisaged.
