Antibodies capable to selectively detect prion PrP Sc isoforms

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专利权人:

发明人:

申请号：

EP00111108.7

公开号：

EP1158003B2

申请日:

2000.05.23

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention pertains to novel antibodies directed to the C-terminal part of the PrPSc isoform of prions. In particular, the present invention pertains to the use of such antibodies in the diagnosis of bovine spongiform encephalopathy (BSE) and the new variant form of Creutzfeld Jacobs Disease (vCJD). In addition, the present invention relates to the peptide recognized by the antibodies and its use in the immunization and/or treatment of BSE, CJD, vCJD and other TSE related diseases.

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