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PANAXATRIOL SAPONINS ENTERIC PELLET, CAPSULE COMPRISING SAME AND METHOD FOR PREPARING SAME
专利权人:
发明人:
申请号:
EP11820998.0
公开号:
EP2612659A1
申请日:
2011.09.01
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Disclosed are a panaxatriol saponins enteric pellet and a method for preparing same, and a capsule comprising the enteric pellet. The enteric pellet comprises a core having a diameter of 20-24 mesh consisting of panaxatriol saponins and pharmaceutical necessities, and an enteric coating layer over the core, wherein the panaxatriol saponins, the pharmaceutical necessities and the enteric coating layer are in a weight ratio of 100:(165-208):(45-65). Preferred pharmaceutical necessities consist of microcrystalline cellulose, starch and polyvidone K30 in a weight ratio of (80-100):(80-100):(5-6), or consist of microcrystalline cellulose, micronized silica gel and polyvidone K30 in a weight ratio of 100:100:8. Preferred enteric pellet has the following components and weight ratio thereof of panaxatriol saponins : microcrystalline cellulose : starch : polyvidone K30 : enteric coating layer = 100:93:93:5.7:58.3, or panaxatriol saponins : microcrystalline cellulose : micronized silica gel : polyvidone K30 : enteric coating layer = 100:100:100:8:62. The enteric pellet is prepared by fluid-bed method or extrusion-spheronization method.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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