Park, John,Flores, Jose Luis Gutierres,Castillejos, David,Aragon, Gabriel Arthuro Carpio,Karageozian, Vicken
申请号:
AU2011254081
公开号:
AU2011254081A1
申请日:
2011.12.15
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2011254081A120120119.pdf#####C.\NRPont,1\DCC\FM340W _1 DOC-I/12/2"11 ABSTRACT Methods and preparations for treating disorders of the eye and/or causing dissolution of corneal proteoglycans and organized healing of corneal stroma, softening of the cornea for non-surgical refractive correction of eyesight, removing corneal haze and opacification, inhibiting fibroblasts and preventing corneal fibrosis and scar formation, treating pterigiums and treating corneal neovascularization as well as iris neovascularization. Preparations containing a) urea, b) urea derivatives (e.g., hydroxyurea, thiourea), c) antimetabolites, e) urea, urea derivatives, non-enzymatic proteins, nucleosides, nucleotides and their derivatives (e.g., adenine, adenosine, cytosine, cytidine, guanine, guanitadine, guanidinium, guanidinium chloride, guanidinium salts, thymidine, thymitadine, uradine, uracil, cysteine), reduced thioctic acid, uric acid, calcium acetyl salicylate, ammonium sulfate, isopropyl alcohol, ethanol, polyethylene glycol, polypropylene glycol or other compounds capable of causing nonenzymatic dissolution of the corneal protoeglycans or f) any of the possible combinations thereof, are administered to the eye in therapeutically effective amounts.