Compounds of the formula (I) ** Formula ** in which: n is the number 0, 1, 2 or 3； Y is -C (O) - or -S (O) 2-； R1 is hydrogen, halogen, cyano, alkyl, haloalkyl, hydroxy, alkoxy, haloalkoxy, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, -NR7R8, -C (O) -NR7R8 or -S (O) 2-R7； said alkyl, haloalkyl and alkoxy are optionally substituted by one, two or three independent R5 moieties； and said cycloalkyl, heterocycloalkyl, aryl and heteroaryl are optionally substituted by one, two or three independent R6 moieties； R2, R3, R4 are independently hydrogen, halogen, alkyl, haloalkyl, hydroxy, alkoxy or haloalkoxy； R5 is cyano, hydroxy, alkoxy, cycloalkyl, heterocycloalkyl, aryl or heteroaryl, said cycloalkyl, heterocycloalkyl, aryl and heteroaryl are optionally substituted by one, two or three independent moieties R6； R6 is halogen, cyano, alkyl, haloalkyl, hydroxyalkyl, hydroxy, alkoxy, haloalkoxy, oxo, cycloalkyl, heterocycloalkyl, aryl or heteroaryl； R7, R8 are independently hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, heterocycloalkyl, heterocycloalkylalkyl, aryl, aryl substituted by halogen or heteroaryl； pharmaceutically acceptable salts and esters thereof； and the deuterated analogues thereof.Compuestos de la fórmula (I)**Fórmula** en la que: n es el número 0, 1, 2 ó 3； Y es -C(O)- o -S(O)2-； R1 es hidrógeno, halógeno, ciano, alquilo, haloalquilo, hidroxi, alcoxi, haloalcoxi, cicloalquilo, heterociclo-alquilo, arilo, heteroarilo, -NR7R8, -C(O)-NR7R8 o -S(O)2-R7； dichos alquilo, haloalquilo y alcoxi están opcionalmente sustituidos por uno, dos o tres restos independientes R5； y dichos cicloalquilo, heterocicloalquilo, arilo y heteroarilo están opcionalmente sustituidos por uno, dos o tres restos independientes R6； R2, R3, R4 son con independencia hidrógeno, halógeno, alquilo, haloalquilo, hidroxi, alcoxi o haloalcoxi； R5 es ciano, hidroxi, alcoxi, cicloalquilo, heterocicloalquilo, arilo o heteroarilo, dichos cicloalquilo, heterocicloalquilo, arilo y heteroarilo están op
