DAROUT, ETZER,达洛 亚瑟,達洛 亞瑟,MCCLURE, KIM FRANCIS,麦克露尔 金,麥克露爾 金,PIOTROWSKI, DAVID WALTER,帕欧卓斯基 大卫,帕歐卓斯基 大衛,RAYMER, BRIAN,瑞莫尔 布莱恩,瑞莫爾 布萊恩
申请号：
TW104132710
公开号：
TW201627302A
申请日:
2015.10.05
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
The present invention is directed at substituted amide compounds, pharmaceutical compositions containing such compounds and the use of such compounds to reduce plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.本發明關於經取代之醯胺化合物、含有此等化合物之醫藥組成物及此等化合物之用途,該用途係用於降低血漿脂質濃度(諸如LDL-膽固醇和三酸甘油酯)且據此治療哺乳動物(包括人類)由於高濃度LDL-膽固醇和三酸甘油酯而惡化之疾病,諸如動脈硬化及心血管疾病。
