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Oral preparations containing therapeutic and adverse agents
专利权人:
ユーロ-セルティーク;エス.エイ.;ユーロ-セルティーク エス.エイ.
发明人:
ライト,カーチス,IV,カーパンゾ,アンソニー,イー.,ライト,カーチス,IV,カーパンゾ,アンソニー,イー.
申请号:
JP2008295477
公开号:
JP5485538B2
申请日:
2008.11.19
申请国别(地区):
JP
年份:
2014
代理人:
摘要:
The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent. The adverse-effect agent is covered with a coating that is substantially insoluble in the gastrointestinal tract. In one embodiment, the adverse-effect agent is coated with an outer base-soluble layer and an inner acid-soluble layer. The therapeutic agent can be uncoated or can be coated with a coating having an outer acid-soluble layer and an inner base-soluble layer. The dosage form discourages administration of the therapeutic agent by other than oral administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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