Carmela Luangdilok,Douglas R. Flanagan,Luk-Chiu Li,Matthew Widman
申请号：
US12636227
公开号：
US08455508B2
申请日:
2009.12.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
An oil-in-water buprenorphine formulation including buprenorphine and a surfactant that emulsifies the buprenorphine in oil, wherein the drug release is controlled by varying the oil concentration and/or pH. A buprenorphine aqueous suspension formulation including a free base buprenorphine and a suspension stabilizer. A buprenorphine oil formulation including a buprenorphine salt suspended in a pharmaceutically acceptable oil. Methods of providing sustained release of buprenorphine over a period of time.
