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COMPOSITION FOR IMPROVING EFFICIENCY OF DRUG DELIVERY
专利权人:
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
发明人:
MARDOR, YAEL,RAM, ZVI
申请号:
EP05789465
公开号:
EP1807146A4
申请日:
2005.09.29
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Method and composition suitable for administering by direct convective interstitial infusion are disclosed. The method comprises: placing at least one direct convective interstitial infusion catheter in contact with the tissue, and pressuring the composition through the catheter. The composition is in a liquefied form having a viscosity above a predetermined value. The predetermined value is selected so as to improve infusion of the compositions into interstitial volumes of the tissue, while minimizing backflow of the compositions along an outer wall of the catheter or leakage into low resistance paths. It is demonstrated that high viscosity results in higher treatment efficiency.
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