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Reversible covalent linkage of functional molecules
专利权人:
UCL Business Plc
发明人:
Mark Smith,Stephen Caddick,James Baker,Vijay Chudasama
申请号:
US15045906
公开号:
US10174094B2
申请日:
2016.02.17
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to the use of a compound containing a moiety of formula (I) as a reagent for linking a compound of formula R1—H which comprises a first functional moiety of formula F1 to a second functional moiety of formula F2wherein X, X′, Y, R1, F1 and F2 are as defined herein. The present invention also provides related processes and products. The present invention is useful for creating functional conjugate compounds, and specifically conjugates in which at least one of the constituent molecules carries a thiol group.
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