Antikine antibodies that bind to multiple CC chemokines

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专利权人:

Dan Allison;Carol Raport

发明人:

Dan Allison,Carol Raport

申请号：

US12870573

公开号：

US08313747B2

申请日:

2010.08.27

申请国别(地区):

US

年份:

2012

代理人:

摘要：

An antikine antibody binds to two, three, four, five or more CC chemokines, such as RANTES/CCL5, MIP-1α/CCL3, MIP-1β/CCL4, or MCP-1/CCL2. Methods for affinity maturation and humanization of antikine antibodies as well as the production of hybridoma cell lines producing antikine antibodies by sequential immunization are also disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/