The present invention provides an improving respiratory health probiotic strain, composition thereof and use thereof. The probiotic strain is a new Lactobacillus helveticus (BCRC910846), which itself and its metabolites can inhibit the bacterial growth, improve the repair ability of lung epithelial cells, and promote the phagocytic ability of macrophages to effectively reduce the chance of infection in the respiratory tract, improve the repair ability of the respiratory tract, and promote the elimination of PM2.5 in the human body and remove foreign matter from the respiratory tract. Wherein the Lactobacillus helveticus metabolites of the present invention contains an effective component of 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid.本發明提供一種改善呼吸道健康之益生菌株及其組合物與用途，該益生菌係為一種新穎的瑞士乳桿菌(編號為BCRC910846)，其本身以及其代謝產物具有抑制細菌生長、提升肺臟上皮細胞之修復、以及促進巨噬細胞之吞噬的能力，而能夠有效減少呼吸道之感染機率、提升呼吸道之修復能力、以及促進排除人體內PM2.5，並能移除呼吸道之異物。其中本發明之瑞士乳桿菌的代謝產物中具有1,2,3,4-四氫-β-咔啉-3-羧酸之效性成分。
