Michael KEIL;Jon J. LONGLET;Oliver KUHN;Carsten Gröning;Martin SUKOPP
发明人:
Martin SUKOPP,Oliver KUHN,Carsten Gröning,Michael KEIL,Jon J. LONGLET
申请号：
US13585233
公开号：
US20120309806A1
申请日:
2012.08.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a process for the of a pyrazole derivative, characterized in that 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile (II) is reacted with a sulfinylating agent selected from trifluoromethylsulfinic acid, trifluoromethylsulfinic acid anhydride, and a trifluoromethylsulfinate alkaline or alkaline earth metal salt and mixtures of the acid and/or the salt(s), in the presence of at least one amine acid complex wherein the amine(s) are selected from tertiary amines and the acid(s) are selected from hydrofluoric, hydrochloric, hydrobromic and hydroiodic acid and sulfonic acid derivatives, and with the addition of a halogenating agent.
