The invention disclosed herein relates to a polymer conjugate characterized in that the backbone of the polymer is an anionic polymer and hydrophobic moieties are covalently attached to the backbone of the polymer, a polymer micelle derived from the polymer conjugate, a composition comprising the polymer micelle, and a method for treating a disease or condition using thereof.本文所揭示之發明係關於一種聚合物共軛物,該聚合物共軛物特徵在於聚合物之主鏈為陰離子聚合物且疏水性部分共價連接於該聚合物之主鏈;一種衍生自聚合物共軛物的聚合物微胞;一種包含聚合物微胞的組合物;以及一種使用上述物質治療疾病或病狀的方法。