A compound of formula (I): Or its salts or pharmaceutically acceptable derivatives thereof wherein: A represents a chemical moiety with the general formula (II): X and Y are independently selected from a group consisting of CH2, CH(R5) or C(R5)(R6)； R1 is selected from the group consisting of optionally substituted arylalkyl, and optionally substituted heteroarylalkyl； R2 is selected from the group consisting of optionally substituted aryl or optionally substituted heteroaryl or NR7R8； R3 R4 R5 R6 R7 and R8 are as defined herein, n=0, 1, 2 or 3； o=0, 1 or 2, with the proviso that when o=0, then n is 1, 2 or 3 and when o=1, then n is 1 or 2 is provided. Pharmaceutical compositions comprising the compounds are also provided. These compounds are useful in the treatment of various disorders including arrhythmia.
