A microneedle sheet is disclosed that comprises a plurality of microneedles formed on a sheet generally along a principal surface of the sheet, wherein the microneedles contain a water-soluble polysaccharide and water, the water content is 1 mass% or more and less than 19 mass% based on the total mass of the microneedles, and the microneedles are raised from the principal surface by bending the sheet.