Richard J. Porambo,Chitrananda Abeygunawardana,Luwy Kavuka Musey,Michael J. Kosinski,Yadong Adam Cui
申请号:
US16645023
公开号:
US20200282040A1
申请日:
2018.09.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these N serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Steptococcus pneumoniae serotypes.