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PNEUMOCOCCAL POLYSACCHARIDES AND THEIR USE IN IMMUNOGENIC POLYSACCHARIDE-CARRIER PROTEIN CONJUGATES
专利权人:
Merck Sharp &; Dohme Corp.
发明人:
Richard J. Porambo,Chitrananda Abeygunawardana,Luwy Kavuka Musey,Michael J. Kosinski,Yadong Adam Cui
申请号:
US16645023
公开号:
US20200282040A1
申请日:
2018.09.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides capsular polysaccharides from Streptococcus pneumoniae serotypes identified using NMR. The present invention further provides polysaccharide-protein conjugates in which capsular polysaccharides from one or more of these serotypes are conjugated to a carrier protein such as CRM197. Polysaccharide-protein conjugates from one or more of these N serotypes may be included in multivalent pneumococcal conjugate vaccines having polysaccharides from multiple additional Steptococcus pneumoniae serotypes.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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