PURPOSE: A pharmaceutical composition containing mixture of ginseng extract and Dimocarpus longan Lour. extract is provided to prevent and reduce physical/mental symptoms due to stress. CONSTITUTION: A pharmaceutical composition for anti-stress contains a mixture of ginseng extract and Dimocarpus longan Lour. extract. The ginseng extract is Panax ginseng, red ginseng, or raw ginseng. The pharmaceutical composition for anti-stress contains the mixture and a pharmaceutically acceptable carrier. A health food for anti-stress contains the mixture and a food additive.본 발명은 삼 추출물과 용안육 추출물의 혼합물 및 이를 포함하고 스트레스에 의해 생기는 정신적·신체적 증상을 예방 및 경감하는 작용을 나타내는 항스트레스용 약제학적 조성물에 관한 것이다.