"pharmaceutical composition, composition and use"

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专利权人:

F. HOFFMANN ROCHE AG

发明人:

JOHN FREDERICK BOYLAN,STANISLAW M. MIKULSKI

申请号：

BR112013010061

公开号：

BR112013010061A2

申请日:

2011.11.04

申请国别(地区):

BR

年份:

2019

代理人:

摘要：

The present invention relates to a combination therapy of 2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N&prime；-(2,2,3,3,3-pentafluoro-propyl)-malonamide, or a pharmaceutically-acceptable salt thereof, and bevacizumab for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example a brain tumor.

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