A needle guide system is provided. The needle guide system includes a puncture device, an ultrasound transducer, a first orientation detector, a second orientation detector, a proximity detector and a processor. The ultrasound transducer is configured to obtain an ultrasound image. The first orientation detector is disposed on the puncture device, and the second orientation detector is disposed on the ultrasound transducer. The proximity detector is disposed on at least one of the puncture device and the ultrasound transducer, configured to obtain a relative distance between the puncture device and the ultrasound transducer. The processor is configured to obtain a spatial relationship between the puncture device and the ultrasound transducer by using the first orientation detector, the second orientation detector, and the proximity detector, and predict the trajectory of the puncture device in the ultrasound image according to the spatial relationship. In addition, a medical intervention system is also provided.一種入針導引系統，包括穿刺裝置、超音波探頭、第一方向感測器、第二方向感測器、近接感測器以及處理器。超音波探頭用以取得超音波影像。第一方向感測器設置於穿刺裝置，第二方向感測器設置於超音波探頭。近接感測器設置於穿刺裝置與超音波探頭的至少其中之一，用以取得穿刺裝置與超音波探頭之間的相對距離。處理器用以藉由第一方向感測器、第二方向感測器以及近接感測器取得穿刺裝置以及超音波探頭之間的空間關係，並且依據所取得的空間關係預測穿刺裝置於超音波影像中的入針軌跡。此外，一種介入治療系統亦被提出。
