THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
KOCHENDERFER, JAMES NOBLE
申请号：
SG11201406414W
公开号：
SG11201406414WA
申请日:
2013.03.15
申请国别(地区):
SG
年份:
2014
代理人:
摘要：
The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells.
