PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF
Ayman ALLIAN,Thomas B. BORCHARDT,Jayanthy JAYANTH,Patrick J. MARROUM,Peter T. MAYER,Mathew M. MULHERN,Fredrik Lars Nordstrom,Ahmad Y. SHEIKH
申请号：
US16905667
公开号：
US20200317682A1
申请日:
2020.06.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.
