Kenneth L. Urish,Matthew G. Keffalas,Timothy J. Mosher,David J. Miller
申请号:
US14971782
公开号:
US20160213278A1
申请日:
2015.12.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A method for detecting symptomatic osteoarthritis in a human patient who is otherwise asymptomatic comprises: taking a plurality of magnetic resonance (MR) image signal features from MR sequences in a joint of the patient submitting the MR image signal features to a classifier for performing a feature reduction for redundant or unnecessary features which are then eliminated calculating a signal texture index (STI) value from the remaining image features comparing that STI value against two population databases, one for individuals known to develop osteoarthritis and a second for individuals known not to develop osteoarthritis at a given time point prognosticating from the STI value, a likelihood of the patient developing osteoarthritis and treating the patient accordingly.