The Board of Trustees of the Leland Stanford Junior University
发明人:
Karl Deisseroth,Polina Anikeeva
申请号:
US16267144
公开号:
US20190217118A1
申请日:
2019.02.04
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are compositions comprising lanthanide-doped nanoparticles which upconvert electromagnetic radiation from infrared or near infrared wavelengths into the visible light spectrum. Also provided herein are methods activating light-responsive opsin proteins expressed on plasma membranes of neurons and selectively altering the membrane polarization state of the neurons using the light delivered by the lanthanide-doped nanoparticles.