Described is a process for the production of a pharmaceutical preparation comprising 5 difluormethoxy-2-[(3,4- dimethoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazole - pantoprazole, a salt thereof, a solvate of pantoprazole or a salt thereof, comprising freeze drying of an aqueous solution consisting of pantoprazole, a salt thereof, a solvate of pantoprazole or a salt thereof, ethylenediamine tetraacetic acid and/or a suitable salt thereof and sodium hydroxide and/or sodium carbonate, as a lyophilized pharmaceutical preparation obtainable by said process, pantoprazole injections and an injection kit.Described is a process for the production of a pharmaceutical preparation comprising 5 difluormethoxy-2-[(3,4- dimethoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazole - pantoprazole, a salt thereof, a solvate of pantoprazole or a salt thereof, comprising freeze drying of an aqueous solution consisting of pantoprazole, a salt thereof, a solvate of pantoprazole or a salt thereof, ethylenediamine tetraacetic acid and/or a suitable salt thereof and sodium hydroxide and/or sodium carbonate, as a lyophilized pharmaceutical preparation obtainable by said process, pantoprazole injections and an injection kit.