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1-SUBSTITUTED 1,2,3,4-TETRAHYDRO-1,7-NAPHTHYRIDIN-8-AMINE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR ANTAGONISTS
专利权人:
TAKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
Dinesh BARAWKAR,Anil M DESHPANDE,Santosh PATIL,Yogesh WAMAN,Anil PANMAND,Dilip JADHAV,Bheemashankar KULKARNI
申请号:
US15746828
公开号:
US20180215754A1
申请日:
2016.07.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a compound represented by the formula (I):wherein each symbol is as defined in the specification, or a salt thereof has an EP4 receptor antagonistic action, and is useful as an agent for the prophylaxis or treatment of EP4 receptor associated diseases (e.g., rheumatoid arthritis, aortic aneurysm (e.g. abdominal aortic aneurysm, thoracic aortic aneurysm, thoracoabdominal aortic aneurysm etc.), endometriosis, ankylosing spondylitis, inflammatory breast cancer etc.) and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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