USE OF FLT3 CAR-T CELLS AND FLT3 INHIBITORS TO TREAT ACUTE MYELOID LEUKEMIA

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专利权人:

JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG

发明人:

Michael HUDECEK,Hardikkumar JETANI

申请号：

US16633132

公开号：

US20200206266A1

申请日:

2018.08.01

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention generally relates to the treatment of cancer with FLT3 targeting agents and kinase inhibitors. In particular, the invention relates to adoptive immunotherapy of Acute Myeloid Leukemia (AML) with chimeric antigen receptor (CAR)-modified T cells specific for FMS-like tyrosine kinase (FLT3) in combination with FLT3 inhibitors.

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