Method of predicting the clinical response to cisplatin or carboplatin chemotherapeutic treatment

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专利权人:

Rafael Rosell Costa

发明人:

Rafael Rosell Costa,Miguel Taron Roca

申请号：

US11908796

公开号：

US08377888B2

申请日:

2006.03.16

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Method for predicting the survival of a patient suffering from NSCLC to a cisplatin or carboplatin based chemotherapy treatment which comprises the step of determining the methylation state of a nucleic acid encoding 14-3-3 sigma in a biological sample from the patient, wherein the presence of methylation is indicative of longer survival of said patient as a response to said chemotherapy treatment. The methylation status of the 14-3-3 sigma gene can be easily determined in a serum sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/