A METHOD FOR PRODUCING STABLE AMORPHOUS HYBRID NANOPARTICLES COMPRISING AT LEAST ONE PROTEIN KINASE INHIBITOR AND AT LEAST ONE POLYMERIC STABILIZING AND MATRIX FORMING COMPONENT.
BRISANDER MAGNUS,DEMIRBÜKER MUSTAFA,JESSON GÉRALD,MALMSTEN MARTIN,DÉRAND HELENE
申请号:
IN6529DEN2014
公开号:
IN6529DEN2014A
申请日:
2014.08.04
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to the field of methods for providing components of pharmaceutical compositions comprising poorly water soluble drugs. In particular the present invention relates to methods for providing stable amorphous hybrid nanoparticles comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix forming component useful in pharmaceutical compositions.