ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
发明人:
WIlliam Tyler
申请号：
US16618101
公开号：
US20200107725A1
申请日:
2018.06.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Methods, systems, and devices for mechanically disturbing tissues of the central nervous system including a brain of a subject are provided. An elastogram of brain tissue may be generated using mesoscopic wavelength ultrasound composed of longitudinal waves in brain tissues to produce micromechanical disturbances of brain nuclei and circuits for characterization of their mechanical properties (e.g., stiffness, elasticity, rigidity, viscoelasticity). A magnetic resonance elastography (MRE) system includes an MRE engine in electronic communication with at least one transducer and with a magnetic resonance imaging (MRI) device. The MRE engine is configured to electronically control operation of the at least one transducer to emit ultrasound, to electronically receive, from the MRI device, at least one signal indicative of measurements of displacement of the brain tissue by the ultrasound, and to electronically generate an elastogram of the brain tissue based on the at least one signal.
