NAGY ESZTER,BADARAU ADRIANA,ROUHA HARALD,STULIK LUKAS,VISRAM ZEHRA
申请号:
IN201727041061
公开号:
IN201727041061A
申请日:
2017.11.16
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
An anti Staphylococcus aureus antibody combination preparation comprising a) a toxin cross neutralizing antibody comprising at least one polyspecific binding site that binds to alpha toxin (Hla) and at least one of the bi component toxins selected from the group consisting of HIg AB HIg CB LukSF LukED Luk S Hlg B LukSD HIg A LukD HIg A LukF Luk EF LukE Hlg B HIg C LukD and HIg C LukF and b) an anti Luk GH antibody and/or c) an OPK antibody which recognizes a S. aureus surface protein thereby inducing OPK specifically an anti Ig binding protein (IGBP) antibody comprising at least one CDR binding site recognizing any of the S. aureus Ig G binding domains of Protein A or Sbi.