Disclosed is an apparatus or device for making knots in a flexible element that engages a medical device, such as an IUD, and associated methods. The knot tying device receives the medical device in a loading element, and then threads the flexible member through an aperture of the medical device using a spooling element. A looping element and knotting element ties the flexible member into a knot. The devices, systems and methods can create a double loop surgeon's knot that are reproducible during the manufacturing process.L'invention concerne un appareil ou dispositif pour faire des noeuds dans un élément flexible qui vient en prise avec un dispositif médical, tel qu'un DIU, et des procédés associés.