TAO, ZHI-FU,DOHERTY, GEORGE,WANG, XILU,SULLIVAN, GERARD M.,SONG, XIAOHONG,KUNZER, AARON R.,WENDT, MICHAEL D.,MARIN, VIOLETA L.,FREY, ROBIN R.,CULLEN, STEVE C.,WELCH, DENNIE S.,SHEN, XIAOQIANG,BENNETT,
申请号:
CA2970155
公开号:
CA2970155A1
申请日:
2015.12.09
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present disclosure concerns Bcl-xL inhibitors having low cell permeability, antibody drug conjugates (ADCs) comprising the inhibitors, synthons useful for synthesizing the ADCs, compositions comprising the inhibitors or ADCs, and various methods of using the inhibitors and ADCs.