DAS PRATAP KUMAR,GOSWAMI SUCHANDRA,CHINNIAH ANNALAKSHMI,RAO JANASWAMY MADHUSUDANA,KATRAGADDA SURESH BABU
申请号：
ZA201106443
公开号：
ZA201106443B
申请日:
2011.09.01
申请国别(地区):
ZA
年份:
2012
代理人:
摘要：
The present invention relates to flavanoid compounds of general formula (X1) wherein: R1 is selected from a group consisting of morpholinyl, N-methyl piperizinyl, piperidinyl and N,N&prime；-dimethylamino groups, and n ranges from 3 to 6, and process for preparation thereof. The present invention relates to the demonstration of anti Helicobacter pylori activity and gastric antisecretory activity of semisynthetically designed flavonoid compounds, to be used for the prevention and treatment of gastroduodenal disorders in general and peptic ulcer diseases in particular. The present invention also relates to a hetero-dimeric bi-functional molecule that can be used as monotherapy substituting/replacing/overcoming currently used triple/quadruple therapy, thereby implicating/anticipating/envisaging its commercial applicability.
