A variant form of urate oxidase and use thereof

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专利权人:

Inc.;Savient Pharmaceuticals

发明人:

Hartman, Jacob,Mendelovitz, Simona

申请号：

AU2011257764

公开号：

AU2011257764B2

申请日:

2011.12.19

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2011257764B220120405.pdf#####ABSTRACT The present invention relates to genetically modified proteins with uricolytic activity. More specifically, the inventions relates to proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidases.1/8 (HaeII) 1 NdeI 113 AlwN Ill Ir s d l origin pigKS-AN Apal NdeI pOUR-P- A N-ks-1 mcs pe ba) 1045 AatlI I 10 (MscI/ScaL) 2629 TetR Figure 1.

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