A computer-based method for screening unknown subjects for COVID-19, including steps of recording at least one voice clip from a screened subject, pre-processing the screened subject voice clip, computing a spectrogram of the pre-processed screened subject voice clip, extracting a feature vector from said screened subject spectrogram, applying a machine learning classifier of a COVID-19 vocal biomarker on the extracted screened subject feature vector thereby receiving a COVID-19 vocal biomarker value, and outputting that the screened subject is COVID-19 positive or COVID-19 negative, based on the COVID-19 vocal biomarker value. The step of extracting the feature vector employs a pre-trained deep convolutional neural network.