JOHNSON, PAUL DAVID,LEACH, ANDREW,LUKE, RICHARD WILLIAM ARTHUR,MATUSIAK, ZBIGNIEW STANLEY,MORRIS, JEFFREY JAMES
申请号:
HRP20140807
公开号:
HRP20140807T1
申请日:
2014.08.26
申请国别(地区):
HR
年份:
2014
代理人:
摘要:
The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I), methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).