The present invention relates to crystal forms B, C and D of Ribociclib succinate salt and derivatives thereof, and their preparation method and composition. The crystal forms B, C and D of Ribociclib succinate salts are obtained by adding 7-cyclopentyl-N,N-dimethyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide solution into succinic acid solution for reaction, stirring the solution under high temperature, filtering the solution after cooling off.本發明係關於一種瑞博西尼琥珀酸鹽(Ribociclib succinate salt)晶型B、C及D與其衍生物，及其製造方法與藥物組合物；該瑞博西尼琥珀酸鹽(Ribociclib succinate salt)晶型B、C及D係將含有7-環戊基-2-(5-呱嗪-1-基-吡啶-2-基氨基)-7H-吡咯並-[2,3-D]嘧啶-6-羧酸二甲基醯胺之有機溶液，緩慢加入琥珀酸之有機溶液反應，並於高溫下攪拌，冷卻過濾所獲得。
