Universite de Liege;Universite Libre de Bruxelles;Femalon S.A.
发明人:
Piette, Marie,Evrard, Brigitte,Coia, Isabelle
申请号:
AU2012285969
公开号:
AU2012285969A1
申请日:
2012.07.13
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to lyophilized compositions comprising cidofovir, hydroxypropyl methylcellulose (HPMC) or hydroxyethylcellulose (HEC) and optionally a plasticizer. In particular, the present invention relates to such compositions which form a sheet-shaped porous solid matrix. The invention also relates to methods for producing such compositions. The invention further relates to such compositions for use in treating human papillomavirus (HPV) infections and HPV-associated malignancies, in particular HPV lesions and cervical cancer.