The present invention relates to mixtures comprising: i) at least one lipid and/or at least one oil； and ii) an alkyl ammonium EDTA salt； wherein the mixture has a water content in the range of 0 to 1.0 wt%. The invention further relates to mixtures which are pre-formulations, methods of treatment comprising administration of such pre-formulations, to pre-filled administration devices and kits containing the formulations, to the use of an alkylammonium EDTA salt to reduce the decomposition of the lipid components and/or any active agent contained within the pre-formulation, and to alkyl ammonium EDTA salts as described herein.本發明係關於混合物，其包含：i)至少一脂質以及/或至少一油；以及ii)一烷基銨EDTA鹽類；其中該混合物具有介於0至1.0wt%範圍之水分含量。本發明更進一步關於為預配方之混合物、包括投予前述預配方之治療方法、包含該配方之預填投藥裝置及套組、烷基銨EDTA鹽類在降低脂質成分以及/或任何包含於該預配方內活性物質之分解之使用。
