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COMBINATION TREATMENT WITH ANTIBODY-DRUG CONJUGATES AND PARP INHIBITORS
专利权人:
IMMUNOGEN, INC.;HEALTH RESEARCH, INC.
发明人:
Eunice Sue Wang,Scott Michael Portwood,Russell Walker
申请号:
US16346950
公开号:
US20200261470A1
申请日:
2017.11.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a method of treating a cancer in a subject comprising administering to the subject an effective amount of a CD33-targeted antibody-drug conjugate (ADC) and an effective amount of a poly-ADP ribose polymerase (PARP) inhibitor. Also provided are pharmaceutical compositions comprising an effective amount of a CD33-targeted ADC and an effective amount of a PARP inhibitor.
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