ARIZONA BOARD OF REGENTS; A BODY CORPORATE OF THE STATE OF ARIZONA; ACTI NG FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
发明人:
PETTIT, GEORGE R.,LIPPERT, JOHN W., III
申请号:
CA2407675
公开号:
CA2407675C
申请日:
2001.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to the syntheses and structural elucidation ofCombretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrugsand the utilization of those prodrugs in the treatment of neoplastic diseases.The prodrugs described herein have the structure: Combretastin A-1 PhosphateProdrug (I) and Combretastin B-1 Phosphate Prodrug (II).