LYOPHILIZED COMPOSITION, AND METHODS TO PRODUCE A LIOFILIZED COMPOSITION AND TO PRODUCE AN IMMUNOLOGICAL COMPOSITION.

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专利权人:

GLAXONSMITHKLINE BIOLOGICALS S.A.

发明人:

DOMINIQUE INGRID LEMOINE

申请号：

BRPI0811228

公开号：

BRPI0811228A2

申请日:

2008.05.22

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention provides lyophilised compositions comprising an antigen and a Toll-like receptor (TLR) 9 agonist. Such compositions may be reconstituted into immunogenic compositions for use in vaccination with a carrier selected from the group of particulate carriers consisting of liposomes, mineral salts, emulsions, polymers and ISCOMs. Methods of making immunogenic compositions from the lyophilised compositions of the invention and use of the same in immunisation are also herein provided.

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