Jacques Bailly,Cornelia Hertel,Daniel Hunziker,Christian Lerner,Ulrike Obst Sander,Jens-Uwe Peters,Philippe Pflieger,Tanja Schulz-Gasch
申请号:
US12210247
公开号:
US08143280B2
申请日:
2008.09.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds of formula Iwherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.